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Founded in 2015 in Guatemala City, the Invariantes Fund invests in technology startups based in the US and Latin America, across different market segments. It is the only VC based in Guatamala, and bills itself as the country’s first early-stage VC firm. As of June 2021, its portfolio includes 24 startups. Invariantes’ most recent investments include participation in the $21m Series A round of US edtech player Reforge, as well in the $130m Series B round of US-based Axiom Space, which is building the first international commercial space station. Both investments were in February 2021.

Samsung Venture Investment, or Samsung Ventures, is the VC investment arm of South Korean diversified conglomerate Samsung Group. It is a separate entity from Samsung NEXT.Samsung Ventures primarily invests in semiconductors, telecommunications tech, software and internet companies, as well as biotechnology and medical companies. The VC is built to support new innovations that can lead to further improvements in Samsung’s existing businesses, which includes smartphones, home appliances, and components like OLED panels and Li-ion batteries.Samsung Ventures has invested in healthcare and wellness tech companies like Indonesia’s telehealth service Alodokter, posture correction device makers Posture360, and Noom, an app for dieting and exercise. In the sensors front, Samsung Ventures has invested in Sense Photonics, a startup creating 3D computer vision based on lidar for industrial and automotive (self-driving) purposes. Besides these companies, Samsung Ventures has also invested in insurtech companies and even gaming companies, such as Pokémon Go developer Niantic.

Focused on life sciences, OrbiMed has been investing in the global healthcare industry for over 20 years. Its portfolio ranges from early-stage startups to multinational corporations. With more than 100 scientific, medical, and investment professionals, it manages over $17bn assets worldwide.

Headquartered in Hong Kong, Summer Capital was founded by senior UBS banker Joseph Chee in 2015. Focused on both public and private investments, it mainly invests in sectors of healthcare, consumer products, education, logistics and fintech. 

PayPal is the US-based online payments company founded in 1999 and acquired by eBay in 2002. It is listed in NASDAQ under the ticker code PYPL.Besides facilitating online payments and money transfers for many e-commerce companies and other internet-based businesses, it is famous for its network of former founders and other alumni, many of whom went on to establish successful companies or became investors in the tech and internet industries. Some famous names linked to this network, sometimes called “PayPal Mafia”, include ex-CEO Peter Thiel, Elon Musk, Dave McClure (founder of 500 Startups), and Reid Hoffman (LinkedIn co-founder).PayPal has invested in several companies, including ride-hailing firms Gojek and Uber and e-commerce platform MercadoLibre. It has also established PayPal Ventures as a separate VC arm and PayPal Incubator to support early-stage startups.

Launched in 2013, Japan’s Rakuten Capital is the corporate venture capital arm of conglomerate Rakuten. It manages a range of funds, such as the early-stage Rakuten Ventures, Rakuten Fintech Fund, and Rakuten Mobility Investments. Its portfolio covers a broad range of companies, including C2C e-commerce platform Carousell, ride-hailing unicorn Gojek, and video game vouchers platform CodaPay. Notable exits include the IPOs of US-based ride hailing company Lyft and image sharing site Pinterest.

Xora Innovation is a subsidiary of the Singapore sovereign investment fund, Temasek. It was established as an early-stage deeptech investment platform that identifies startups connected with the Singapore science and technology ecosystem (although the startup can be based anywhere in the world). Xora plans to invest as a lead or co-lead in seed or Series A rounds, with later-stage investments being handled through Temasek. As of July 2021, Xora has invested in two companies based in Singapore: Allozymes, which provides enzyme engineering services, and Nuevocor, which is developing gene therapy for certain heart diseases.

TI Platform Management is a US-based investment firm founded by Alex Bangash and Trang T Nguyen, who are also the founders of LP network and investment news platform TrustedInsight. Founded in 2015, the firm seeks out disruptive business models and invests in a range of categories, from furniture and home construction to healthcare and deep-tech. It has invested in Singapore-based enzyme engineering startup Allozymes, B2B pharmacy fulfillment service TruePill, and supply chain management startup Tyltgo.

Founded in San Francisco in 2009, Eniac Ventures is an early-stage investor in diverse sectors. It currently has 59 startups in its portolio. The vast majority of its exits have been via acquisitions by larger companies such as Anchor sold to Spotify. The VC also invested in Airbnb and Medallia that went public in 2020 and 2019 respectively.Recent investments in June 2021 include co-leading the $4.2m seed round of US mental healthcare platform Nirvana Health and participation in the $30m Series B round of Briq, a US financial planning and workflow automation platform for the construction industry. The VC also joined in the Series A round of Vence, the California-based producer of smart wearables for livestock management.

Founded in Boston in 2019, Transformation is entirely dedicated to healthcare disruption, predominently focuses on US investments and typically invests $10-30m per startup. It currently has 22 companies in its portfolio.  Its most recent investments include in the June 2021 $85m Series C round of Portuguese home physiotherapy tech solution SWORD Health, the world’s fastest-growing musculoskeletal solution, and, the same month, in the $21m Series D round of Protenus, the US’ leading healthcare compliance analytics firm.

Set up in 2002 by Patrice Hoppenot 15 years after he founded European investment fund BC Partners, Investisseurs & Partenaires (I&P) is an impact investor seeking to help SMEs prosper in Africa and create sustainable jobs and income there. With about €210m raised to date, I&P finances SMEs, startups and regional investment funds in Africa through equity participation and loans, as well as through microfinance institutions. Its I&P Acceleration Technologies focuses on digital startups with €2.5m of funding to be invested in 10–15 startups in 2020–2023. To date, I&P has supported more than 100 capital-funded companies and 20 companies benefiting from subsidized acceleration programs. I&P has about 100 staff based in Paris, Washington D.C. and in seven African offices (Burkina Faso, Cameroon, Côte d'Ivoire, Ghana, Madagascar, Niger and Senegal).

Future Positive Capital is a Paris-based VC with a second office in London. Its investments cover deep-technology companies applying AI, biotechnology, synthetic biology, as well as robotics. Co-funded in 2016 by ex-Index Ventures associate Sofia Hmich along with Alexandre Terrien and Michael Rosen; it has made 18 investments to date. In 2019 Future Positive raised over $57m pan-European impact investment fund, claiming that most European VCs are continuing to staying focused on sectors, such as consumer, fintech, and marketing, or web and mobile technologies. Future Positive’s belief is that there is instead, a long-tail of investment opportunities to back businesses that actually tackle “the world’s most pressing problems”.Through this fund, it will back throughout Seed and Series A stages, with the possibility to follow up on Series B investing between around €300,000 and €5m. Since then the company has backed startups in the like of BioBeats, an AI company focused on preventative mental health, cell-based startup Meatable, and more recently NotCo, the Chilean unicorn disrupting the food and beverage sector with AI-enabled plant-based products.The team counts on an extensive network of mentors, innovators, impact angel investors and entrepreneurs such as F1 pilots Nico Rosberg, the MD of Alibaba France Sebastien Badault, the Omid Ashtari the President of Citymapper amongst others.

Founded in 1997 in London, Amadeus has invested in more than 130 companies, has over 40 employees and has raised over $1bn to date.  The investor focuses on early-stage UK-based companies, although it has also invested in later-stage European and developing market startups.  In August 2021, it announced a $150m upcoming investment drive in Brazil. Amadeus currently has 54 portfolio companies. Its recent investments include the June 2021 £20m Series A investment round of UK-based XYZ Reality that employs holograms in construction tech. In May 2021, it led the $4.8m investment in the cryptography lifecycle management platform Cryptosense.

Founded in Hong Kong in 2018, Lake Bleu Capital currently operates in both Hong Kong and Shanghai. With assets worth billions of US dollars under management, it mainly invests in pharmaceuticals, biotech, medical devices and healthcare services companies in Asia, especially Greater China. Its limited partners include sovereign wealth funds, university endowments, foundations, pension funds, and family offices across the world.With a long-term investment strategy, Lake Bleu Capital invests through both public and private equity with a focus on mid- to late-stage companies.

Founded in 2017, Suzhou Longmen Ventures mainly invests in businesses working on innovative drugs and medical devices. It manages tens of billions RMB in assets. 

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